fbpx

ICSI with microinjection of morphologically selected sperm

One of the most innovative techniques in the world of human fertility is the IMSI, or microinjection of morphologically selected spermatozoa.

This test is known with the English acronym MSOME (Motile Sperm Organelle Morphology Examination). The oocyte micro-injection of spermatozoa selected with this high-resolution optical system is known as IMSI.

The IMSI allows injecting the oocytes only with selected spermatozoa according to strict morphological criteria in which the size, shape of the head, middle part of the sperm and the presence of vacuoles in the head are considered.

A correlation has been established between the presence of large vacuoles in the sperm head and DNA fragmentation. It is thus believed that the IMSI “deselects” spermatozoa with physiological abnormalities associated with DNA fragmentation. Thus, up to 68% of “normal” spermatozoa selected to be injected under a lesser optical resolution do not meet the criteria for selection of IMSI.

A recent meta-analysis showed that the use of IMSI significantly increases the percentage of embryonic implantation (OR 2.72; 95% CI 1.50-4.95) and pregnancy (OR 3.12; 95% CI 1.55-6.26) and reduces the risk of abortion (OR 0.42; 95% CI 0.23-0.78) in comparison with ICSI. Randomized studies have also shown that couples with failed ICSI cycles associated with poor sperm quality achieve term pregnancies after IMSI.

If you need more information about this treatment.

Contact us in our lines:

  • Medellín: +57(4) 268 80 00
  • Bogotá: +57(1) 746 98 69
  • Cartagena: +57(5) 693 04 34
  • Pereira: +57(6) 340 17 09
  • Whatsapp: +57 316 3033866

Or in our social networks on Facebook and Instagram.

  • Learn more by taking the first step – All you have to do is fill in the following form

    I accept the INSER data processing policy
  • Nuestras Sedes

    Medellín

    Tel. +57(604) 268 8000 Calle 12 No. 39-60 Sector El Poblado.

    Bogotá​

    Tel. +57(601) 746 9869 Calle 124 No. 7-38, piso 7. Unidad de Especialistas Santa Fe Real.

    Cartagena

    Tel. +57(605) 693 0434 Calle 6a No. 3-17 Edificio Jasban, consultorio 401.

    Pereira

    Tel. +57(606) 340 1709 Calle 10 No. 15-48, piso 2. Cat Médica, Barrio Los Alpes

    Acreditaciones:

    Somos parte del Cluster de Servicios:

    2020© inSer – Instituto de Fertilidad Humana