Testicular biopsy

To corroborate a diagnosis of infertility and other problems in male sexual health, in many cases, a doctor can recommend a testicular biopsy to diagnose the man’s reproductive potential

What is testicular biopsy?

It is a surgery to remove a piece of tissue from the testicles. This tissue is examined under a microscope.

The biopsy can be done in many ways. These are:

  • Open biopsy: In this procedure, the skin of the testicle is cleaned with a disinfectant medication (antiseptic). The area is then covered, and a local anesthetic is applied. A small incision is then performed through the skin, and a small sample of testicular tissue is extracted. In the end, a stitch is placed to close the wound. If necessary, the procedure is repeated in the other testicle.
  • Puncture biopsy: The area is cleaned, and local anesthesia is used, as in the open biopsy. A sample of the testicle is taken using a special needle. This procedure does not require skin incisions.

This procedure is often commonly practiced while diagnosing the cause of male infertility. It is performed when a sperm analysis suggests that there are abnormal sperm and other problems that may interfere with reproduction in men. In some cases, sperm obtained from a testicular biopsy can be used to perform an in vitro fertilization or IVF.

The risks of a testicular biopsy are:

  • Bleeding
  • Infection
  • Pain
  • Inflammation


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